Description
Testosterone propionate 100
is an oil based solution of testosterone propionate for IM injection designed to reach peak testosterone
serum levels within 24 hours of IM administration and remain elevated for 2 to 3 days. testosterone
propionate 100 is suitable for the treatment of hypogonadism and other disorders related to androgen
deficiency.
testosterone propionate 100 has both anabolic and androgenic effects. Testosterone supplementation has
been demonstrated to increase strength and growth of new muscle tissue, frequently with increases
in libido.
INDICATIONS
Adult Males: testosterone propionate 100 Injection is indicated for replacement therapy in conditions
associated with a deficiency or absence of endogenous testosterone.
Primary hypogonadism: Testicular failure due to cryptorchidism, bilateral torsion, orchitis,
vanishing testis syndrome, or orchidectomy.
Hypogonadotropic hypogonadism: Idiopathic gonadotropin or LHRH deficiency, or
pituitary-hypothalamic injury from tumors, trauma, or radiation.
ADVERSE REACTIONS
Male: Gynecomastia, excessive frequency and duration of penile erections, oligospermia.
Skin and Appendages: Hirsutism, male pattern baldness and acne, gynecomastia.
Fluid/electrolyte Disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic
phosphates.
Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests; rarely, hepatocellular
neoplasms, peliosis hepatitis, hepatic adenomas, and cholestatic hepatitis.
Hematologic: Suppression of clotting factors II, V, VII, & X; bleeding in patients on anti-coagulant
therapy.
Nervous System: Increased or decreased libido, headache, anxiety, depression, and generalized
paresthesia.
Other: Serum lipid changes, hypercalcaemia, hypertension, oedema, priapism, and potentiation of sleep
apnea.
PRECAUTIONS
Because androgens may alter serum cholesterol concentration, caution should be used when administering
these drugs to patients with a history of myocardial infarction or coronary artery disease.
Patients on oral anticoagulant therapy require close monitoring especially when androgens are started or
stopped.
Diabetics: androgens may alter the metabolism of oral hypoglycemic agents or may change insulin
sensitivity in patients with diabetes mellitus which may require adjustment of dosage of insulin and other
hypoglycemic drugs.
Adult Male: 50 – 100mg injected IM every 2 to 3 days or as directed by physician.
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