Drostanolone propionate is a synthetic derivative of dihydrotestosterone, producing an anabolic effect and
promoting protein synthesis as well as creating positive nitrogen balance in humans. Since it is a derivative
of dihydrotestosterone, drostanolone does not aromatize to estrogens. drostanolone 76 have significant
anabolic and androgenic properties promoting an increase in strength and growth of muscle tissue while
acting as an estrogen antagonist.
The combination of a short-acting propionate ester with a long-acting enanthate ester produces rapid
increases in serum drostanolone levels with a sustained duration of 5-8 days.
To rapidly restore muscle tissue atrophied during recovery from a traumatic injury.
To offset muscle catabolism in patients with a wasting syndrome.
To treat certain types of anemia which are non-responsive to first line agents.
Oestrogen antagonist in treatment of breast cancer.
Male: Gynecomastia, excessive frequency and duration of penile erections, oligospermia.
Skin and Appendages: Hirsutism, male pattern baldness and acne, gynecomastia.
Fluid/electrolyte Disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic
Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests; rarely, hepatocellular
neoplasms, peliosis hepatitis, hepatic adenomas, and cholestatic hepatitis.
Hematologic: Suppression of clotting factors II, V, VII, & X; bleeding in patients on anti-coagulant therapy.
Nervous System: Changes in libido, aggression, headache, anxiety, depression, and generalized paresthesia.
Metabolic: reduced glucose tolerance, increased creatinine clearance, and inhibition of gonadotrophin
Other: Serum lipid changes, hypercalcaemia, hypertension, oedema, priapism, and potentiation
of sleep apnea
Adult male: 100 – 150mg injected IM every 3-5 days for duration of 4-8 weeks.